Expert Reports

These reports are unique, authoritative expert evaluations. Each report is produced by a committee of experts selected by the Academy to address a particular statement of task and is subject to a rigorous, independent peer review.

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Application of Modern Toxicology Approaches for Predicting Acute Toxicity for Chemical Defense (2015)

The US Department of Defense (DOD) is faced with an overwhelming task in evaluating chemicals that could potentially pose a threat to its deployed personnel. There are over 84,000 registered chemicals, and testing them with traditional toxicity-testing methods is not feasible in terms of time or money. In recent years, there has been a concerted effort to develop new approaches to toxicity testing that incorporate advances in systems biology... More >>

Review of California's Risk-Assessment Process for Pesticides (2015)

This report reviews the risk-assessment practices used by the California Department of Pesticide Regulation as part of its mission to ensure the protection of workers and public health. Overall, the study finds that the Department of Pesticide Regulation's risk-characterization documents are comprehensive and follow established risk-assessment practices. However, the bulk of the assessments duplicate much of the work of the US Environmenta... More >>

Sustainability Concepts in Decision-Making: Tools and Approaches for the US Environmental Protection Agency (2014)

Population growth, climate change, and greater consumption of natural resources are just a few of the challenges the US Environmental Protection Agency (EPA) faces in pursuing its mission to protect human health and the environment. The agency has increasingly embraced the use of sustainability tools and approaches for considering the potential social, environmental, and economic effects of agency decisions and actions. This report identifie... More >>

Report in Brief

Rethinking the Components, Coordination, and Management of the U.S. Environmental Protection Agency Laboratories (2014)

As an agency with the mission and regulatory responsibility to protect human health and the environment, the US Environmental Protection Agency (EPA) requires substantial high-quality in-house scientific expertise and laboratory capabilities so that it can answer questions related to regulation, enforcement, and environmental effects of specific chemicals, activities, and processes. EPA’s laboratory system consists of a distributed network o... More >>

Review of the Formaldehyde Assessment in the National Toxicology Program 12th Report on Carcinogens (2014)

In 1981, the National Toxicology Program (NTP) listed formaldehyde in the 2nd Report on Carcinogens (RoC) as "reasonably anticipated to be a human carcinogen." In 2011, NTP upgraded the listing of formaldehyde in the 12th RoC to "known to be a human carcinogen." Following the new listing, Congress directed the Department of Health and Human Services to arrange for the National Academy of Sciences to independently review formaldehyde’s substanc... More >>

Report in Brief