Expert Report

Twelfth Interim Report of the Subcommittee on Acute Exposure Guideline Levels (2005)

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Extremely hazardous substances (EHSs), as defined in the Superfund Amendments and Reauthorization Act of 1986, can be released accidentally as a result of chemical spills, industrial explosions, fires, or accidents involving railroad cars or trucks transporting these substances, or intentionally through terrorist activities. It is also feasible that these substance can be released by improper storage and/or handling. Workers and residents in communities surrounding industrial facilities where EHSs are manufactured, used, or stored and in communities along the nation's railways and highways are potentially at risk of being exposed to airborne EHSs during accidental and intentional releases. This report provides technical guidance on establishing community Acute Exposure Guideline Levels (AEGLs) for certain hazardous chemicals. It reviews the scientific validity of AEGLs developed by the national Advisory Committee on Acute Exposure Guideline Levels for Hazardous Substances, identifies research priorities, and identifies guidance issues that may require modification or further development based on the toxicological database for the chemicals reviewed. This twelfth interim report offers recommendations for improving AEGLs for the following 15 chemicals: toluene, xylenes, ammonia, bromine, aniline, methyl ethyl ketone, hydrazine, iron pentacarbonyl, phosphine, chlorine trifluoride, ethyleneimine, propyleneimine, allyl alcohol, ethylene oxide, and nickel carbonyl.

About this Report

Primary Board:

Board on Environmental Science and Toxicology

Other Report(s) in this series:

Thirteenth Interim Report of the Subcommittee on Acute Exposure Guideline Levels (2005)
Fourteenth Interim Report of the Committee on Acute Exposure Guideline Levels (2006)
Acute Exposure Guideline Levels for Selected Airborne Chemicals: Volume 5 (2007)
Acute Exposure Guidelines Levels for Selected Airborne Chemicals, Volume 6 (2008)
Sixteenth Interim Report of the Committee on Acute Exposure Guideline Levels (2009)
Seventeenth Interim Report of the Committee on Acute Exposure Guideline Levels (2010)
Acute Exposure Guideline Levels for Selected Airborne Chemicals: Volume 8 (2009)
Eighteenth Interim Report of the Committee on Acute Exposure Guideline Levels (2010)
Nineteenth Interim Report of the Committee on Acute Exposure Guideline Levels: Part A (2011)
Nineteenth Interim Report of the Committee on Acute Exposure Guideline Levels: Part B (2011)
Twentieth Interim Report of the Committee on Acute Exposure Guideline Levels: Parts A and B (2011)
Acute Exposure Guideline Levels for Selected Airborne Chemicals: Volume 10 (2011)
Acute Exposure Guideline Levels for Selected Airborne Chemicals: Volume 11 (2012)
Acute Exposure Guideline Levels for Selected Airborne Chemicals: Volume 12 (2012)
Twenty-first Interim Report of the Committee on Acute Exposure Guideline Levels: Parts A and B (2012)
Acute Exposure Guideline Levels for Selected Airborne Chemicals: Volume 13 (2013)
Acute Exposure Guideline Levels for Selected Airborne Chemicals: Volume 14 (2013)
Twenty-second Interim Report of the Committee on Acute Exposure Gudeline Levels (2013)
Acute Exposure Guideline Levels for Selected Airborne Chemicals: Volume 15 (2013)